My biggest concern is our midfield without Xhaka. Say what you want about Xhaka, he is a presence physically - even if he hasn't used it well in the past.
With (likely) Torreira and Guendouzi in there, I think that they will target Douzi and try and bully him. That's what I would do if I was Mourinho. (thank fudge I am not).
I like Douzi but he's prone to at least one big mistake a game, especially under pressure.