Yes, absolutely. Such depth in the league, with a lot of former Juventus, Milan, Inter, Napoli, Roma etc youth who maybe never realised their full potential as well as the most promising youngsters in the country. Of course it is a large league so some teams won't stack up vs A-league teams, but the top ones would certainly do a job.
I don't think people realise how ruthless and tactical the game can be in Italy.