The rise of Isis is the direct result of the west meddling in the ME
Yes. Just like Al Qaeda before them.
ISIS never would have banded together without western influence. The groups that make up ISIS were a large number of small warring factions prior to that. They mostly hated each other. They needed funds, arms, and mediation, to come together and be as powerful as they became. All of which came from the US and their western friends.
Al Qaeda was not formed with the west meddling in the ME. It started in 1988 with a meeting of Bin Laden, Zawahiri and a doctor Fadl in
Peshawar Pakistan.
Bin Laden was angered that in 1990 US forces arrived in Saudi Arabia after offering them him mujahideen to defend the kingdom from Saddam Hussein. He then left for Sudan where he made public attacks on the Royal Family.
In 1992 Al Qaeda's first bomb attack was in Aden. That was the start of many outrages against civilians.