99% Invisible has been one of my favourites recently, I download a bunch of episodes each week and listen on the way to/from uni. All about architecture and design. Really well made.
Serial and Criminal are both well made also. I really liked both seasons of Serial but like others have mentioned the first is a lot easier to get in to.
I listen to a bunch of Guardian podcasts as well, there's probably at least a couple that she would like. I usually go for Football Weekly, Politics Weekly, Science Weekly, Chips With Everything (Technology podcasts) and What Would a Feminist Do?